Ergosterol peroxide from marine fungus Phoma sp. induces ROS-dependent apoptosis and autophagy in human lung adenocarcinoma cells

As part of our ongoing search for novel therapeutic structures from microorganism, the chemical examination of marine fungus Phoma sp. resulted in the isolation of ergosterol, ergosterol peroxide (EP), and 9,11-dehydroergosterol peroxide (DEP). The bioassay results demonstrated that the three isolat...

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Detalles Bibliográficos
Autores principales: Wu, Han-Ying, Yang, Feng-Ling, Li, Lan-Hui, Rao, Yerra Koteswara, Ju, Tz-Chuen, Wong, Wei-Ting, Hsieh, Chih-Yu, Pivkin, Michael V., Hua, Kuo-Feng, Wu, Shih-Hsiung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298985/
https://www.ncbi.nlm.nih.gov/pubmed/30560887
http://dx.doi.org/10.1038/s41598-018-36411-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298985/
https://www.ncbi.nlm.nih.gov/pubmed/30560887
http://dx.doi.org/10.1038/s41598-018-36411-2

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