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TAC-seq: targeted DNA and RNA sequencing for precise biomarker molecule counting

Targeted next-generation sequencing (NGS) methods have become essential in medical research and diagnostics. In addition to NGS sensitivity and high-throughput capacity, precise biomolecule counting based on unique molecular identifier (UMI) has potential to increase biomolecule detection accuracy....

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Detalles Bibliográficos
Autores principales: Teder, Hindrek, Koel, Mariann, Paluoja, Priit, Jatsenko, Tatjana, Rekker, Kadri, Laisk-Podar, Triin, Kukuškina, Viktorija, Velthut-Meikas, Agne, Fjodorova, Olga, Peters, Maire, Kere, Juha, Salumets, Andres, Palta, Priit, Krjutškov, Kaarel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299075/
https://www.ncbi.nlm.nih.gov/pubmed/30588329
http://dx.doi.org/10.1038/s41525-018-0072-5