Interleukin 2 modulates thymic-derived regulatory T cell epigenetic landscape

Foxp3(+)CD4(+) regulatory T (T(reg)) cells are essential for preventing fatal autoimmunity and safeguard immune homeostasis in vivo. While expression of the transcription factor Foxp3 and IL-2 signals are both required for the development and function of T(reg) cells, the commitment to the T(reg) ce...

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Detalles Bibliográficos
Autores principales: Chorro, Laurent, Suzuki, Masako, Chin, Shu Shien, Williams, Tere M., Snapp, Erik L., Odagiu, Livia, Labrecque, Nathalie, Lauvau, Grégoire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299086/
https://www.ncbi.nlm.nih.gov/pubmed/30560927
http://dx.doi.org/10.1038/s41467-018-07806-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299086/
https://www.ncbi.nlm.nih.gov/pubmed/30560927
http://dx.doi.org/10.1038/s41467-018-07806-6

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