Cargando…
A Model for Human Islet Transplantation to Immunodeficient Streptozotocin-Induced Diabetic Mice
Streptozotocin (STZ) is a cytotoxic glucose analogue that causes beta cell death and is widely used to induce experimental diabetes in rodents. The sensitivity of beta cells to STZ is species-specific and human beta cells are resistant to STZ. In experimental islet transplantation to rodents, STZ-di...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299193/ https://www.ncbi.nlm.nih.gov/pubmed/30269527 http://dx.doi.org/10.1177/0963689718801006 |