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A Model for Human Islet Transplantation to Immunodeficient Streptozotocin-Induced Diabetic Mice
Streptozotocin (STZ) is a cytotoxic glucose analogue that causes beta cell death and is widely used to induce experimental diabetes in rodents. The sensitivity of beta cells to STZ is species-specific and human beta cells are resistant to STZ. In experimental islet transplantation to rodents, STZ-di...
Autores principales: | Estil·les, Elisabet, Téllez, Noèlia, Nacher, Montserrat, Montanya, Eduard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299193/ https://www.ncbi.nlm.nih.gov/pubmed/30269527 http://dx.doi.org/10.1177/0963689718801006 |
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