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Ex Vivo Generation of Donor Antigen-Specific Immunomodulatory Cells: A Comparison Study of Anti-CD80/86 mAbs and CTLA4-lg Costimulatory Blockade

Adoptive transfer of alloantigen-specific immunomodulatory cells generated ex vivo with anti-CD80/CD86 mAbs (2D10.4/IT2.2) holds promise for operational tolerance after transplantation. However, good manufacturing practice is required to allow widespread clinical application. Belatacept, a clinicall...

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Detalles Bibliográficos
Autores principales: Watanabe, M., Kumagai-Braesch, Makiko, Yao, M., Thunberg, S., Berglund, D., Sellberg, F., Jorns, C., Enoksson, S. Lind, Henriksson, J., Lundgren, T., Uhlin, M., Berglund, E., Ericzon, B.-G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299197/
https://www.ncbi.nlm.nih.gov/pubmed/30261751
http://dx.doi.org/10.1177/0963689718794642