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Exosomes Derived from IDO1-Overexpressing Rat Bone Marrow Mesenchymal Stem Cells Promote Immunotolerance of Cardiac Allografts

BACKGROUND: The immunosuppressive activity of mesenchymal stem cells (MSCs) has been exploited to induce tolerance after organ transplantation. The indoleamine 2,3-dioxygenase (IDO) may have beneficial effects in the immunoregulatory properties of MSCs. It was recently revealed that exosomes derived...

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Detalles Bibliográficos
Autores principales: He, Ji-Gang, Xie, Qiao-Li, Li, Bei-Bei, Zhou, Liang, Yan, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299201/
https://www.ncbi.nlm.nih.gov/pubmed/30311501
http://dx.doi.org/10.1177/0963689718805375