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Intrinsic Class D β-Lactamases of Clostridium difficile

Clostridium difficile is the causative agent of the deadly C. difficile infection. Resistance of the pathogen to β-lactam antibiotics plays a major role in the development of the disease, but the mechanism of resistance is currently unknown. We discovered that C. difficile encodes class D β-lactamas...

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Detalles Bibliográficos
Autores principales: Toth, Marta, Stewart, Nichole K., Smith, Clyde, Vakulenko, Sergei B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299217/
https://www.ncbi.nlm.nih.gov/pubmed/30563905
http://dx.doi.org/10.1128/mBio.01803-18