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Genome-wide DNA Methylation and RNAseq Analyses Identify Aberrant Signalling Pathways in Focal Cortical Dysplasia (FCD) Type II

Focal cortical dysplasia (FCD) is one of the most common pathologies associated with drug-resistant epilepsy (DRE). The pharmacological targets remain obscured, as the molecular mechanisms underlying FCD are unclear. Implications of epigenetically modulated aberrant gene expression in disease progre...

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Detalles Bibliográficos
Autores principales: Dixit, Aparna Banerjee, Sharma, Devina, Tripathi, Manjari, Srivastava, Arpna, Paul, Debasmita, Prakash, Deepak, Sarkar, Chitra, Kumar, Krishan, Banerjee, Jyotirmoy, Chandra, P. Sarat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299275/
https://www.ncbi.nlm.nih.gov/pubmed/30568293
http://dx.doi.org/10.1038/s41598-018-35892-5