Hybrid Hydrogel Composed of Polymeric Nanocapsules Co-Loading Lidocaine and Prilocaine for Topical Intraoral Anesthesia

This study reports the development of nanostructured hydrogels for the sustained release of the eutectic mixture of lidocaine and prilocaine (both at 2.5%) for intraoral topical use. The local anesthetics, free or encapsulated in poly(ε-caprolactone) nanocapsules, were incorporated into CARBOPOL hyd...

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Detalles Bibliográficos
Autores principales: Muniz, Bruno Vilela, Baratelli, Diego, Di Carla, Stephany, Serpe, Luciano, da Silva, Camila Batista, Guilherme, Viviane Aparecida, Ribeiro, Lígia Nunes de Morais, Cereda, Cintia Maria Saia, de Paula, Eneida, Volpato, Maria Cristina, Groppo, Francisco Carlos, Fraceto, Leonardo Fernandes, Franz-Montan, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299281/
https://www.ncbi.nlm.nih.gov/pubmed/30568251
http://dx.doi.org/10.1038/s41598-018-36382-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299281/
https://www.ncbi.nlm.nih.gov/pubmed/30568251
http://dx.doi.org/10.1038/s41598-018-36382-4

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