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Vinculin and the mechanical response of adherent fibroblasts to matrix deformation

Cells respond to the mechanics of their environment. Mechanical cues include extracellular matrix (ECM) stiffness and deformation, which are primarily sensed through integrin-mediated adhesions. We investigated the impact of ECM deformation on cellular forces, measuring the time-evolution of tractio...

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Detalles Bibliográficos
Autores principales: Rosowski, Kathryn A., Boltyanskiy, Rostislav, Xiang, Yingjie, Van den Dries, Koen, Schwartz, Martin A., Dufresne, Eric R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299284/
https://www.ncbi.nlm.nih.gov/pubmed/30568231
http://dx.doi.org/10.1038/s41598-018-36272-9