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Vinculin and the mechanical response of adherent fibroblasts to matrix deformation
Cells respond to the mechanics of their environment. Mechanical cues include extracellular matrix (ECM) stiffness and deformation, which are primarily sensed through integrin-mediated adhesions. We investigated the impact of ECM deformation on cellular forces, measuring the time-evolution of tractio...
Autores principales: | Rosowski, Kathryn A., Boltyanskiy, Rostislav, Xiang, Yingjie, Van den Dries, Koen, Schwartz, Martin A., Dufresne, Eric R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299284/ https://www.ncbi.nlm.nih.gov/pubmed/30568231 http://dx.doi.org/10.1038/s41598-018-36272-9 |
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