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Is the History Repeated? Can (2R,6R)-Hydroxynorketamine be Another Antidepressant?

Historically, identification of active metabolites has contributed to drug discovery for psychiatric disorders. It has led to the identification of new medications such as desipramine (a metabolite of imipramine) and paliperidone (a metabolite of risperidone). (R,S)-Ketamine, which has been regarded...

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Detalles Bibliográficos
Autores principales: Chaki, Shigeyuki, Yamaguchi, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299292/
https://www.ncbi.nlm.nih.gov/pubmed/30573991
http://dx.doi.org/10.1177/1179069518815445