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Genetic polymorphisms of UGT1A1 and susceptibility to anti-tuberculosis drug-induced liver: A RUCAM-based case–control study

Uridine 5’-diphospho-glucuronosyl-transferase 1A1 (UGT1A1) plays an important role in the biliary excretion of bilirubin, suggesting genetic polymorphisms of UGT1A1 may have an impact on bile acid metabolism, which may be related to the development of anti-tuberculosis drug-induced liver injury (ATL...

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Detalles Bibliográficos
Autores principales: Tao, Bilin, Chen, Shixian, Lin, Guancheng, Yang, Miaomiao, Lu, Lihuan, He, Xiaomin, Pan, Hongqiu, Tang, Shaowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299304/
http://dx.doi.org/10.1177/2058738418816288