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Gene code CD274/PD-L1: from molecular basis toward cancer immunotherapy

The programmed death 1 receptor (PD-1) and its ligand (PD-L1) are key molecules of immune checkpoint mechanisms in cancer and actually represent one of the main targets of immunotherapy. The predictive and prognostic values of PD-L1 expression alone in cancer patients is currently under debate due t...

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Detalles Bibliográficos
Autores principales: Fabrizio, Federico Pio, Trombetta, Domenico, Rossi, Antonio, Sparaneo, Angelo, Castellana, Stefano, Muscarella, Lucia Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299305/
https://www.ncbi.nlm.nih.gov/pubmed/30574211
http://dx.doi.org/10.1177/1758835918815598