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Exosomes Derived from Hypoxic Colorectal Cancer Cells Transfer Wnt4 to Normoxic Cells to Elicit a Prometastatic Phenotype

Hypoxia is the most common characteristic of solid tumours driving cancer metastasis. Cancer cells release exosomes with various functions into the tumour microenvironment during cancer progression. However, the roles and associated mechanisms of hypoxic colorectal cancer (CRC) cell-derived exosomes...

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Detalles Bibliográficos
Autores principales: Huang, Zhe, Yang, Mingli, Li, Yunze, Yang, Fan, Feng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299371/
https://www.ncbi.nlm.nih.gov/pubmed/30585272
http://dx.doi.org/10.7150/ijbs.28288