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A heparan sulfate-based matrix therapy reduces brain damage and enhances functional recovery following stroke

Alteration of the extracellular matrix (ECM) is one of the major events in the pathogenesis of brain lesions following ischemic stroke. Heparan sulfate mimetics (HSm) are synthetic pharmacologically active polysaccharides that promote ECM remodeling and tissue regeneration in various types of lesion...

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Detalles Bibliográficos
Autores principales: Khelif, Yacine, Toutain, Jérôme, Quittet, Marie-Sophie, Chantepie, Sandrine, Laffray, Xavier, Valable, Samuel, Divoux, Didier, Sineriz, Fernando, Pascolo-Rebouillat, Emanuelle, Papy-Garcia, Dulce, Barritault, Denis, Touzani, Omar, Bernaudin, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299437/
https://www.ncbi.nlm.nih.gov/pubmed/30613264
http://dx.doi.org/10.7150/thno.28252