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Remote loading of liposomes with a (124)I-radioiodinated compound and their in vivo evaluation by PET/CT in a murine tumor model

Long circulating liposomes entrapping iodinated and radioiodinated compounds offer a highly versatile theranostic platform. Here we report a new methodology for efficient and high-yield loading of such compounds into liposomes, enabling CT/SPECT/PET imaging and (131)I-radiotherapy. Methods: The CT c...

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Detalles Bibliográficos
Autores principales: Engudar, Gokce, Schaarup-Jensen, Henrik, Fliedner, Frederikke P., Hansen, Anders E., Kempen, Paul, Jølck, Rasmus I., Kjaer, Andreas, Andresen, Thomas L., Clausen, Mads H., Jensen, Andreas I., Henriksen, Jonas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299439/
https://www.ncbi.nlm.nih.gov/pubmed/30613265
http://dx.doi.org/10.7150/thno.26706