Cargando…

BPI-9016M, a c-Met inhibitor, suppresses tumor cell growth, migration and invasion of lung adenocarcinoma via miR203-DKK1

Activation of c-Met plays a critical role in tumorigenesis, migration and invasion in lung cancer. Here, we explored the therapeutic efficacy of a novel small-molecule c-Met inhibitor (BPI-9016M) in lung adenocarcinoma and investigated the underlying molecular mechanisms. Method: BPI-9016M, a c-Met...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Panpan, Li, Shaolei, Lv, Chao, Si, Jiahui, Xiong, Ying, Ding, Lieming, Ma, Yuanyuan, Yang, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299440/
https://www.ncbi.nlm.nih.gov/pubmed/30613269
http://dx.doi.org/10.7150/thno.27667