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Human ex vivo 3D bone model recapitulates osteocyte response to metastatic prostate cancer
Prostate cancer (PCa) is the second leading cause of cancer deaths among American men. Unfortunately, there is no cure once the tumor is established within the bone niche. Although osteocytes are master regulators of bone homeostasis and remodeling, their role in supporting PCa metastases remains po...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299475/ https://www.ncbi.nlm.nih.gov/pubmed/30568232 http://dx.doi.org/10.1038/s41598-018-36424-x |