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Human ex vivo 3D bone model recapitulates osteocyte response to metastatic prostate cancer

Prostate cancer (PCa) is the second leading cause of cancer deaths among American men. Unfortunately, there is no cure once the tumor is established within the bone niche. Although osteocytes are master regulators of bone homeostasis and remodeling, their role in supporting PCa metastases remains po...

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Detalles Bibliográficos
Autores principales: Choudhary, Saba, Ramasundaram, Poornema, Dziopa, Eugenia, Mannion, Ciaran, Kissin, Yair, Tricoli, Lucas, Albanese, Christopher, Lee, Woo, Zilberberg, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299475/
https://www.ncbi.nlm.nih.gov/pubmed/30568232
http://dx.doi.org/10.1038/s41598-018-36424-x