Cargando…

Increasing the Capping Efficiency of the Sindbis Virus nsP1 Protein Negatively Affects Viral Infection

Alphaviruses are arthropod-borne RNA viruses that are capable of causing severe disease and are a significant burden to public health. Alphaviral replication results in the production of both capped and noncapped viral genomic RNAs (ncgRNAs), which are packaged into virions during infections of vert...

Descripción completa

Detalles Bibliográficos
Autores principales: LaPointe, Autumn T., Moreno-Contreras, Joaquín, Sokoloski, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299483/
https://www.ncbi.nlm.nih.gov/pubmed/30538185
http://dx.doi.org/10.1128/mBio.02342-18