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EriB targeted inhibition of microglia activity attenuates MPP(+) induced DA neuron injury through the NF-κB signaling pathway

Accumulating evidence indicates that microglia activation is associated with an increased risk for developing Parkinson’s disease (PD). With the progressive and selective degeneration of dopaminergic (DA) neurons, proinflammatory cytokines are elevated in the substantia nigra (SN) of PD patients. Th...

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Detalles Bibliográficos
Autores principales: Dou, Fangfang, Chu, Xinkun, Zhang, Bei, Liang, Liang, Lu, Guoqiang, Ding, Jianqing, Chen, Shengdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299497/
https://www.ncbi.nlm.nih.gov/pubmed/30563578
http://dx.doi.org/10.1186/s13041-018-0418-z