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miRNA-133b targets FGFR1 and presents multiple tumor suppressor activities in osteosarcoma

BACKGROUND: Osteosarcoma (OS) is the most common bone malignancy prevalent in children and young adults. MicroRNA-133b (miR-133b), through directly targeting the fibroblast growth factor receptor 1 (FGFR1), is increasingly recognized as a tumor suppressor in different types of cancers. However, litt...

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Detalles Bibliográficos
Autores principales: Gao, Gan, Tian, Zhen, Zhu, Huan-Ye, Ouyang, Xun-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299514/
https://www.ncbi.nlm.nih.gov/pubmed/30574019
http://dx.doi.org/10.1186/s12935-018-0696-7