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A novel PAX5 rearrangement in TCF3-PBX1 acute lymphoblastic leukemia: a case report

BACKGROUND: Chromosome translocations are a hallmark of B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Additional genomic aberrations are also crucial in both BCP-ALL leukemogenesis and treatment management. Herein, we report the phenotypic and molecular cytogenetic characterization of an...

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Detalles Bibliográficos
Autores principales: Barbosa, Thayana Conceição, Lopes, Bruno Almeida, Blunck, Caroline Barbieri, Mansur, Marcela Braga, Deyl, Adriana Vanessa Santini, Emerenciano, Mariana, Pombo-de-Oliveira, Maria S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299517/
https://www.ncbi.nlm.nih.gov/pubmed/30563523
http://dx.doi.org/10.1186/s12920-018-0444-9