Hybrid peeling for fast and accurate calling, phasing, and imputation with sequence data of any coverage in pedigrees

BACKGROUND: In this paper, we extend multi-locus iterative peeling to provide a computationally efficient method for calling, phasing, and imputing sequence data of any coverage in small or large pedigrees. Our method, called hybrid peeling, uses multi-locus iterative peeling to estimate shared chro...

Descripción completa

Detalles Bibliográficos
Autores principales: Whalen, Andrew, Ros-Freixedes, Roger, Wilson, David L., Gorjanc, Gregor, Hickey, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299538/
https://www.ncbi.nlm.nih.gov/pubmed/30563452
http://dx.doi.org/10.1186/s12711-018-0438-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299538/
https://www.ncbi.nlm.nih.gov/pubmed/30563452
http://dx.doi.org/10.1186/s12711-018-0438-2

Ejemplares similares