Cargando…
Hybrid peeling for fast and accurate calling, phasing, and imputation with sequence data of any coverage in pedigrees
BACKGROUND: In this paper, we extend multi-locus iterative peeling to provide a computationally efficient method for calling, phasing, and imputing sequence data of any coverage in small or large pedigrees. Our method, called hybrid peeling, uses multi-locus iterative peeling to estimate shared chro...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299538/ https://www.ncbi.nlm.nih.gov/pubmed/30563452 http://dx.doi.org/10.1186/s12711-018-0438-2 |