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Adipocyte-derived IL-6 and leptin promote breast Cancer metastasis via upregulation of Lysyl Hydroxylase-2 expression

BACKGROUND: Adipocytes make up the major component of breast tissue, accounting for 90% of stromal tissue. Thus, the crosstalk between adipocytes and breast cancer cells may play a critical role in cancer progression. Adipocyte-breast cancer interactions have been considered important for the promot...

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Detalles Bibliográficos
Autores principales: He, Jin-Yong, Wei, Xiao-Hui, Li, Si-Jing, Liu, Yang, Hu, Hao-Lin, Li, Zheng-Zheng, Kuang, Xin-Hong, Wang, Lai, Shi, Xin, Yuan, Sheng-Tao, Sun, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299564/
https://www.ncbi.nlm.nih.gov/pubmed/30563531
http://dx.doi.org/10.1186/s12964-018-0309-z