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Dichotomy in redundant enhancers points to presence of initiators of gene regulation
BACKGROUND: The regulatory landscape of a gene locus often consists of several functionally redundant enhancers establishing phenotypic robustness and evolutionary stability of its regulatory program. However, it is unclear what mechanisms are employed by redundant enhancers to cooperatively orchest...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299655/ https://www.ncbi.nlm.nih.gov/pubmed/30563465 http://dx.doi.org/10.1186/s12864-018-5335-0 |