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Hypoxia-elicited mesenchymal stem cell-derived exosomes facilitates cardiac repair through miR-125b-mediated prevention of cell death in myocardial infarction

Exosomes (Exo) secreted from hypoxia-conditioned bone marrow mesenchymal stem cells (BM-MSCs) were found to be protective for ischemic disease. However, the role of exosomal miRNA in the protective effect of hypoxia-conditioned BM-MSCs-derived Exo (Hypo-Exo) remains largely uncharacterized and the p...

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Detalles Bibliográficos
Autores principales: Zhu, Ling-Ping, Tian, Tian, Wang, Jun-Yao, He, Jing-Ni, Chen, Tong, Pan, Miao, Xu, Li, Zhang, Hui-xin, Qiu, Xue-Ting, Li, Chuan-Chang, Wang, Kang-Kai, Shen, Hong, Zhang, Guo-Gang, Bai, Yong-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299684/
https://www.ncbi.nlm.nih.gov/pubmed/30613290
http://dx.doi.org/10.7150/thno.28021