Cargando…

Hypoxia-elicited mesenchymal stem cell-derived exosomes facilitates cardiac repair through miR-125b-mediated prevention of cell death in myocardial infarction

Exosomes (Exo) secreted from hypoxia-conditioned bone marrow mesenchymal stem cells (BM-MSCs) were found to be protective for ischemic disease. However, the role of exosomal miRNA in the protective effect of hypoxia-conditioned BM-MSCs-derived Exo (Hypo-Exo) remains largely uncharacterized and the p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Ling-Ping, Tian, Tian, Wang, Jun-Yao, He, Jing-Ni, Chen, Tong, Pan, Miao, Xu, Li, Zhang, Hui-xin, Qiu, Xue-Ting, Li, Chuan-Chang, Wang, Kang-Kai, Shen, Hong, Zhang, Guo-Gang, Bai, Yong-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299684/ https://www.ncbi.nlm.nih.gov/pubmed/30613290 http://dx.doi.org/10.7150/thno.28021

Ejemplares similares

Therapeutic Potential of Exosomes Derived From circRNA_0002113 Lacking Mesenchymal Stem Cells in Myocardial Infarction
por: Tian, Tiantian, et al.
Publicado: (2022)

Advances in the study of exosomes derived from mesenchymal stem cells and cardiac cells for the treatment of myocardial infarction
por: Liu, Yuchang, et al.
Publicado: (2023)

The Application Potential and Advance of Mesenchymal Stem Cell-Derived Exosomes in Myocardial Infarction
por: Wang, Xianyun, et al.
Publicado: (2021)

Exosomes as a Cell-free Therapy for Myocardial Injury Following Acute Myocardial Infarction or Ischemic Reperfusion
por: An, Ziyu, et al.
Publicado: (2022)

CircRNA MFACR Is Upregulated in Myocardial Infarction and Downregulates miR-125b to Promote Cardiomyocyte Apoptosis Induced by Hypoxia
por: Wang, Shujuan, et al.
Publicado: (2021)

Experimental Myocardial Infarction Elicits Time-Dependent Patterns of Vascular Hypoxia in Peripheral Organs and in the Brain
por: David, Hélène, et al.
Publicado: (2021)

Exosomal CircHIPK3 Released from Hypoxia-Induced Cardiomyocytes Regulates Cardiac Angiogenesis after Myocardial Infarction
por: Wang, Yan, et al.
Publicado: (2020)

GATA-4-expressing mouse bone marrow mesenchymal stem cells improve cardiac function after myocardial infarction via secreted exosomes
por: He, Ji-Gang, et al.
Publicado: (2018)

Novel Applications of Mesenchymal Stem Cell-Derived Exosomes for Myocardial Infarction Therapeutics
por: Ozaki Tan, Sho Joseph, et al.
Publicado: (2020)

Sequential transplantation of exosomes and mesenchymal stem cells pretreated with a combination of hypoxia and Tongxinluo efficiently facilitates cardiac repair
por: Xiong, Yuyan, et al.
Publicado: (2022)

Hypoxia-elicited Exosomes Promote the Chemoresistance of Pancreatic Cancer Cells by Transferring LncROR via Hippo Signaling
por: Wang, Huizhi, et al.
Publicado: (2023)

Cardio-renal Exosomes in Myocardial Infarction Serum Regulate Proangiogenic Paracrine Signaling in Adipose Mesenchymal Stem Cells
por: Gao, Lei, et al.
Publicado: (2020)

Exosomes derived from human placental mesenchymal stem cells ameliorate myocardial infarction via anti-inflammation and restoring gut dysbiosis
por: Yang, Libo, et al.
Publicado: (2022)

Author Correction: GATA-4-expressing mouse bone marrow mesenchymal stem cells improve cardiac function after myocardial infarction via secreted exosomes
por: He, Ji-Gang, et al.
Publicado: (2023)

In Situ Preconditioning of Human Mesenchymal Stem Cells Elicits Comprehensive Cardiac Repair Following Myocardial Infarction
por: Sim, Woo-Sup, et al.
Publicado: (2021)

Peripheral Serum Exosomes Isolated from Patients with Acute Myocardial Infarction Promote Endothelial Cell Angiogenesis via the miR-126-3p/TSC1/mTORC1/HIF-1α Pathway
por: Duan, Shasha, et al.
Publicado: (2022)

Exosomes Mediate the Intercellular Communication after Myocardial Infarction
por: Yuan, Ming-Jie, et al.
Publicado: (2016)

Cell Death and Exosomes Regulation After Myocardial Infarction and Ischemia-Reperfusion
por: Wu, Xun, et al.
Publicado: (2021)

Hypoxia-associated genes predicting future risk of myocardial infarction: a GEO database-based study
por: Li, Shaohua, et al.
Publicado: (2023)

Exosomes Derived from Glioma Cells under Hypoxia Promote Angiogenesis through Up-regulated Exosomal Connexin 43
por: Yang, Zhang-Jian, et al.
Publicado: (2022)

Extracellular vesicles from hypoxia-preconditioned mesenchymal stem cells alleviates myocardial injury by targeting thioredoxin-interacting protein-mediated hypoxia-inducible factor-1α pathway
por: Mao, Cheng-Yu, et al.
Publicado: (2022)

Stem cell-derived exosomes in the treatment of acute myocardial infarction in preclinical animal models: a meta-analysis of randomized controlled trials
por: Zheng, Yan-li, et al.
Publicado: (2022)

Fabrication of Tβ4-Exosome-releasing artificial stem cells for myocardial infarction therapy by improving coronary collateralization
por: Chen, Peier, et al.
Publicado: (2022)

Exosomal microRNA‑4516, microRNA‑203 and SFRP1 are potential biomarkers of acute myocardial infarction
por: Liu, Peng, et al.
Publicado: (2023)

Exosomes and Exosomal Cargos: A Promising World for Ventricular Remodeling Following Myocardial Infarction
por: Fang, Jiacheng, et al.
Publicado: (2022)

Emerging Potential of Exosomes on Adipogenic Differentiation of Mesenchymal Stem Cells
por: Zhong, Yuxuan, et al.
Publicado: (2021)

Macrophage migration inhibitory factor facilitates the therapeutic efficacy of mesenchymal stem cells derived exosomes in acute myocardial infarction through upregulating miR-133a-3p
por: Zhu, Wenwu, et al.
Publicado: (2021)

Diagnostic value of miR-30d-5p and miR-125b-5p in acute myocardial infarction
por: JIA, KEGANG, et al.
Publicado: (2016)

Increased Serum CA125 and Brain-Derived Neurotrophic Factor (BDNF) Levels on Acute Myocardial Infarction: A Predictor for Acute Heart Failure
por: Wu, Haibo, et al.
Publicado: (2019)

MicroRNA-132, Delivered by Mesenchymal Stem Cell-Derived Exosomes, Promote Angiogenesis in Myocardial Infarction
por: Ma, Teng, et al.
Publicado: (2018)

Bone marrow mesenchymal stem cell-derived exosomes protect against myocardial infarction by promoting autophagy
por: Zou, Liyuan, et al.
Publicado: (2019)

IFN-γ promoted exosomes from mesenchymal stem cells to attenuate colitis via miR-125a and miR-125b
por: Yang, Ruili, et al.
Publicado: (2020)

Combinatorial treatment of acute myocardial infarction using stem cells and their derived exosomes resulted in improved heart performance
por: Huang, Peisen, et al.
Publicado: (2019)

Bone marrow mesenchymal stem cell-secreted exosomes carrying microRNA-125b protect against myocardial ischemia reperfusion injury via targeting SIRT7
por: Chen, Qi, et al.
Publicado: (2019)

Mesenchymal Stem Cells Inhibits Migration and Vasculogenic Mimicry in Nasopharyngeal Carcinoma Via Exosomal MiR-125a
por: Wan, Fangzhu, et al.
Publicado: (2022)

Dendritic cell-derived exosomal miR-494-3p promotes angiogenesis following myocardial infarction
por: Liu, Haibo, et al.
Publicado: (2021)

Dendritic cell-derived exosomal miR-494-3p promotes angiogenesis following myocardial infarction
por: Liu, Haibo, et al.
Publicado: (2022)

EGR2 is a hub-gene in myocardial infarction and aggravates inflammation and apoptosis in hypoxia-induced cardiomyocytes
por: Bo, Zhixiang, et al.
Publicado: (2022)

IFN-γ enhances the efficacy of mesenchymal stromal cell-derived exosomes via miR-21 in myocardial infarction rats
por: Zhang, Jian, et al.
Publicado: (2022)

Carbohydrate antigen 125 for mortality risk prediction following acute myocardial infarction
por: Falcão, Felipe, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3f2qrm8fb0ko8jllk61aj6kmr7