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P-glycoprotein-targeted photodynamic therapy boosts cancer nanomedicine by priming tumor microenvironment

Cancer nanomedicines only modestly improve the overall survival of patients because their anticancer activity is limited by biological barriers posed by the tumor microenvironment. Currently, all the drugs in FDA-approved cancer nanomedicines are substrates for P-glycoprotein (Pgp), and thus, Pgp-me...

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Detalles Bibliográficos
Autores principales: Mao, Chengqiong, Li, Fang, Zhao, Yan, Debinski, Waldemar, Ming, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299702/
https://www.ncbi.nlm.nih.gov/pubmed/30613297
http://dx.doi.org/10.7150/thno.29580