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P-glycoprotein-targeted photodynamic therapy boosts cancer nanomedicine by priming tumor microenvironment
Cancer nanomedicines only modestly improve the overall survival of patients because their anticancer activity is limited by biological barriers posed by the tumor microenvironment. Currently, all the drugs in FDA-approved cancer nanomedicines are substrates for P-glycoprotein (Pgp), and thus, Pgp-me...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299702/ https://www.ncbi.nlm.nih.gov/pubmed/30613297 http://dx.doi.org/10.7150/thno.29580 |