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Imaging glial activation in patients with post-treatment Lyme disease symptoms: a pilot study using [(11)C]DPA-713 PET

The pathophysiology of post-treatment Lyme disease syndrome (PTLDS) may be linked to overactive immunity including aberrant activity of the brain’s resident immune cells, microglia. Here we used [(11)C]DPA-713 and positron emission tomography to quantify the 18 kDa translocator protein, a marker of...

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Detalles Bibliográficos
Autores principales: Coughlin, Jennifer M., Yang, Ting, Rebman, Alison W., Bechtold, Kathleen T., Du, Yong, Mathews, William B., Lesniak, Wojciech G., Mihm, Erica A., Frey, Sarah M., Marshall, Erica S., Rosenthal, Hailey B., Reekie, Tristan A., Kassiou, Michael, Dannals, Robert F., Soloski, Mark J., Aucott, John N., Pomper, Martin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299943/
https://www.ncbi.nlm.nih.gov/pubmed/30567544
http://dx.doi.org/10.1186/s12974-018-1381-4