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Imaging glial activation in patients with post-treatment Lyme disease symptoms: a pilot study using [(11)C]DPA-713 PET
The pathophysiology of post-treatment Lyme disease syndrome (PTLDS) may be linked to overactive immunity including aberrant activity of the brain’s resident immune cells, microglia. Here we used [(11)C]DPA-713 and positron emission tomography to quantify the 18 kDa translocator protein, a marker of...
Autores principales: | Coughlin, Jennifer M., Yang, Ting, Rebman, Alison W., Bechtold, Kathleen T., Du, Yong, Mathews, William B., Lesniak, Wojciech G., Mihm, Erica A., Frey, Sarah M., Marshall, Erica S., Rosenthal, Hailey B., Reekie, Tristan A., Kassiou, Michael, Dannals, Robert F., Soloski, Mark J., Aucott, John N., Pomper, Martin G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299943/ https://www.ncbi.nlm.nih.gov/pubmed/30567544 http://dx.doi.org/10.1186/s12974-018-1381-4 |
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