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C3G, through its GEF activity, induces megakaryocytic differentiation and proplatelet formation
BACKGROUND: Megakaryopoiesis allows platelet formation, which is necessary for coagulation, also playing an important role in different pathologies. However, this process remains to be fully characterized. C3G, an activator of Rap1 GTPases, is involved in platelet activation and regulates several di...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299959/ https://www.ncbi.nlm.nih.gov/pubmed/30567575 http://dx.doi.org/10.1186/s12964-018-0311-5 |