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C3G, through its GEF activity, induces megakaryocytic differentiation and proplatelet formation

BACKGROUND: Megakaryopoiesis allows platelet formation, which is necessary for coagulation, also playing an important role in different pathologies. However, this process remains to be fully characterized. C3G, an activator of Rap1 GTPases, is involved in platelet activation and regulates several di...

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Detalles Bibliográficos
Autores principales: Ortiz-Rivero, Sara, Baquero, Cristina, Hernández-Cano, Luis, Roldán-Etcheverry, Juan José, Gutiérrez-Herrero, Sara, Fernández-Infante, Cristina, Martín-Granado, Víctor, Anguita, Eduardo, de Pereda, José María, Porras, Almudena, Guerrero, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299959/
https://www.ncbi.nlm.nih.gov/pubmed/30567575
http://dx.doi.org/10.1186/s12964-018-0311-5