Dihomo-γ-linolenic acid inhibits xenograft tumor growth in mice bearing shRNA-transfected HCA-7 cells targeting delta-5-desaturase

BACKGROUND: We previously demonstrated that knockdown of delta-5-desaturase via siRNA transfection together with dihomo-γ-linolenic acid supplementation inhibited colon cancer cell growth and migration, by promoting the production of the anti-cancer byproduct 8-hydroxyoctanoic acid from Cyclooxygena...

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Detalles Bibliográficos
Autores principales: Xu, Yi, Yang, Xiaoyu, Gao, Di, Yang, Liu, Miskimins, Keith, Qian, Steven Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299961/
https://www.ncbi.nlm.nih.gov/pubmed/30567534
http://dx.doi.org/10.1186/s12885-018-5185-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299961/
https://www.ncbi.nlm.nih.gov/pubmed/30567534
http://dx.doi.org/10.1186/s12885-018-5185-9

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