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Dihomo-γ-linolenic acid inhibits xenograft tumor growth in mice bearing shRNA-transfected HCA-7 cells targeting delta-5-desaturase

BACKGROUND: We previously demonstrated that knockdown of delta-5-desaturase via siRNA transfection together with dihomo-γ-linolenic acid supplementation inhibited colon cancer cell growth and migration, by promoting the production of the anti-cancer byproduct 8-hydroxyoctanoic acid from Cyclooxygena...

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Detalles Bibliográficos
Autores principales:	Xu, Yi, Yang, Xiaoyu, Gao, Di, Yang, Liu, Miskimins, Keith, Qian, Steven Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299961/ https://www.ncbi.nlm.nih.gov/pubmed/30567534 http://dx.doi.org/10.1186/s12885-018-5185-9

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