Cell Hashing with barcoded antibodies enables multiplexing and doublet detection for single cell genomics

Despite rapid developments in single cell sequencing, sample-specific batch effects, detection of cell multiplets, and experimental costs remain outstanding challenges. Here, we introduce Cell Hashing, where oligo-tagged antibodies against ubiquitously expressed surface proteins uniquely label cells...

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Detalles Bibliográficos
Autores principales: Stoeckius, Marlon, Zheng, Shiwei, Houck-Loomis, Brian, Hao, Stephanie, Yeung, Bertrand Z., Mauck, William M., Smibert, Peter, Satija, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300015/
https://www.ncbi.nlm.nih.gov/pubmed/30567574
http://dx.doi.org/10.1186/s13059-018-1603-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300015/
https://www.ncbi.nlm.nih.gov/pubmed/30567574
http://dx.doi.org/10.1186/s13059-018-1603-1

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