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Cell Hashing with barcoded antibodies enables multiplexing and doublet detection for single cell genomics
Despite rapid developments in single cell sequencing, sample-specific batch effects, detection of cell multiplets, and experimental costs remain outstanding challenges. Here, we introduce Cell Hashing, where oligo-tagged antibodies against ubiquitously expressed surface proteins uniquely label cells...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300015/ https://www.ncbi.nlm.nih.gov/pubmed/30567574 http://dx.doi.org/10.1186/s13059-018-1603-1 |