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Destabilization of the MiniChromosome Maintenance (MCM) complex modulates the cellular response to DNA double strand breaks
DNA replication during S phase involves thousands of replication forks that must be coordinated to ensure that every DNA section is replicated only once. The minichromosome maintenance proteins, MCM2 to MCM7, form a heteromeric DNA helicase required for both the initiation and elongation of DNA repl...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300108/ https://www.ncbi.nlm.nih.gov/pubmed/30516086 http://dx.doi.org/10.1080/15384101.2018.1553336 |