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T cell cytolytic capacity is independent of initial stimulation strength
How cells respond to a myriad of stimuli with finite signaling machinery is central to immunology. In naive T cells, the inherent effect of ligand strength on activation pathways and endpoints remains controversial, confounded by environmental fluctuations and intercellular variability within popula...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300116/ https://www.ncbi.nlm.nih.gov/pubmed/30013148 http://dx.doi.org/10.1038/s41590-018-0160-9 |