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T cell cytolytic capacity is independent of initial stimulation strength

How cells respond to a myriad of stimuli with finite signaling machinery is central to immunology. In naive T cells, the inherent effect of ligand strength on activation pathways and endpoints remains controversial, confounded by environmental fluctuations and intercellular variability within popula...

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Detalles Bibliográficos
Autores principales:	Richard, Arianne C., Lun, Aaron T. L., Lau, Winnie W. Y., Göttgens, Berthold, Marioni, John C., Griffiths, Gillian M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300116/ https://www.ncbi.nlm.nih.gov/pubmed/30013148 http://dx.doi.org/10.1038/s41590-018-0160-9

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