Guiding the humoral response against HIV-1 toward a MPER adjacent region by immunization with a VLP-formulated antibody-selected envelope variant

Preventive HIV-1 vaccine strategies rely on the elicitation of broadly neutralizing antibody (bNAb) responses, but their induction in vivo by vaccination remains challenging. Considering that the ability of an epitope to elicit effective humoral immunity depends on its exposure on the virion, we hav...

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Detalles Bibliográficos
Autores principales: Beltran-Pavez, Carolina, Ferreira, Carolina B., Merino-Mansilla, Alberto, Fabra-Garcia, Amanda, Casadella, Maria, Noguera-Julian, Marc, Paredes, Roger, Olvera, Alex, Haro, Isabel, Brander, Christian, Garcia, Felipe, Gatell, Jose M., Yuste, Eloisa, Sanchez-Merino, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300218/
https://www.ncbi.nlm.nih.gov/pubmed/30566493
http://dx.doi.org/10.1371/journal.pone.0208345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300218/
https://www.ncbi.nlm.nih.gov/pubmed/30566493
http://dx.doi.org/10.1371/journal.pone.0208345

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