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Elevation in lung volume and preventing catastrophic airway closure in asthmatics during bronchoconstriction

BACKGROUND: Asthma exacerbations cause lung hyperinflation, elevation in load to inspiratory muscles, and decreased breathing capacity that, in severe cases, may lead to inspiratory muscle fatigue and respiratory failure. Hyperinflation has been attributed to a passive mechanical origin; a respirato...

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Detalles Bibliográficos
Autores principales: Osorio-Valencia, Juan S., Wongviriyawong, Chanikarn, Winkler, Tilo, Kelly, Vanessa J., Harris, Robert S., Venegas, Jose G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300269/
https://www.ncbi.nlm.nih.gov/pubmed/30566496
http://dx.doi.org/10.1371/journal.pone.0208337