NKB signaling in the posterodorsal medial amygdala stimulates gonadotropin release in a kisspeptin-independent manner in female mice

Neurokinin B (NKB) signaling is critical for reproduction in all studied species. The existing consensus is that NKB induces GnRH release via kisspeptin (Kiss1) stimulation in the arcuate nucleus. However, the stimulatory action of NKB is dependent on circulating estrogen (E(2)) levels, without whic...

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Detalles Bibliográficos
Autores principales: Fergani, Chrysanthi, Leon, Silvia, Padilla, Stephanie L, Verstegen, Anne MJ, Palmiter, Richard D, Navarro, Victor M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300354/
https://www.ncbi.nlm.nih.gov/pubmed/30565563
http://dx.doi.org/10.7554/eLife.40476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300354/
https://www.ncbi.nlm.nih.gov/pubmed/30565563
http://dx.doi.org/10.7554/eLife.40476

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