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NKB signaling in the posterodorsal medial amygdala stimulates gonadotropin release in a kisspeptin-independent manner in female mice
Neurokinin B (NKB) signaling is critical for reproduction in all studied species. The existing consensus is that NKB induces GnRH release via kisspeptin (Kiss1) stimulation in the arcuate nucleus. However, the stimulatory action of NKB is dependent on circulating estrogen (E(2)) levels, without whic...
Autores principales: | Fergani, Chrysanthi, Leon, Silvia, Padilla, Stephanie L, Verstegen, Anne MJ, Palmiter, Richard D, Navarro, Victor M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300354/ https://www.ncbi.nlm.nih.gov/pubmed/30565563 http://dx.doi.org/10.7554/eLife.40476 |
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