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Preacinetobactin not acinetobactin is essential for iron uptake by the BauA transporter of the pathogen Acinetobacter baumannii

New strategies are urgently required to develop antibiotics. The siderophore uptake system has attracted considerable attention, but rational design of siderophore antibiotic conjugates requires knowledge of recognition by the cognate outer-membrane transporter. Acinetobacter baumannii is a serious...

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Detalles Bibliográficos
Autores principales: Moynié, Lucile, Serra, Ilaria, Scorciapino, Mariano A, Oueis, Emilia, Page, Malcolm GP, Ceccarelli, Matteo, Naismith, James H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300358/
https://www.ncbi.nlm.nih.gov/pubmed/30558715
http://dx.doi.org/10.7554/eLife.42270