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Nanostructures of diamond, graphene oxide and graphite inhibit CYP1A2, CYP2D6 and CYP3A4 enzymes and downregulate their genes in liver cells

INTRODUCTION AND OBJECTIVE: Currently, carbon nanostructures are vastly explored materials with potential for future employment in biomedicine. The possibility of employment of diamond nanoparticles (DN), graphene oxide (GO) or graphite nanoparticles (GN) for in vivo applications raises a question o...

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Detalles Bibliográficos
Autores principales: Strojny, Barbara, Sawosz, Ewa, Grodzik, Marta, Jaworski, Sławomir, Szczepaniak, Jarosław, Sosnowska, Malwina, Wierzbicki, Mateusz, Kutwin, Marta, Orlińska, Sylwia, Chwalibog, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300366/
https://www.ncbi.nlm.nih.gov/pubmed/30587978
http://dx.doi.org/10.2147/IJN.S188997