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A new design for a chronological release profile of etodolac from coated bilayer tablets: In-vitro and in-vivo assessment
Repeated dose medication usually maximizes adverse effects, while sustained release systems did not offer a fast onset of action. Etodolac was formulated to enable pulsatile and sustained drug release, which was chronologically more suitable as an anti-inflammatory drug. Eudragit® RSPO, Eudragit® RL...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300462/ https://www.ncbi.nlm.nih.gov/pubmed/30581611 http://dx.doi.org/10.1016/j.jare.2018.08.003 |