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Metformin Promotes the Protection of Mice Infected With Plasmodium yoelii Independently of γδ T Cell Expansion

Adaptive immune responses are critical for protection against infection with Plasmodium parasites. The metabolic state dramatically changes in T cells during activation and the memory phase. Recent findings suggest that metformin, a medication for treating type-II diabetes, enhances T-cell immune re...

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Detalles Bibliográficos
Autores principales: Miyakoda, Mana, Bayarsaikhan, Ganchimeg, Kimura, Daisuke, Akbari, Masoud, Udono, Heiichiro, Yui, Katsuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300485/
https://www.ncbi.nlm.nih.gov/pubmed/30619302
http://dx.doi.org/10.3389/fimmu.2018.02942