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Metformin Promotes the Protection of Mice Infected With Plasmodium yoelii Independently of γδ T Cell Expansion
Adaptive immune responses are critical for protection against infection with Plasmodium parasites. The metabolic state dramatically changes in T cells during activation and the memory phase. Recent findings suggest that metformin, a medication for treating type-II diabetes, enhances T-cell immune re...
Autores principales: | Miyakoda, Mana, Bayarsaikhan, Ganchimeg, Kimura, Daisuke, Akbari, Masoud, Udono, Heiichiro, Yui, Katsuyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300485/ https://www.ncbi.nlm.nih.gov/pubmed/30619302 http://dx.doi.org/10.3389/fimmu.2018.02942 |
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